The Tiny Organisms Transforming Farming | Karsten Temme | TED
10:26Added Aug 30, 2026
What if the solution to feeding humanity has been hiding in the soil for millions of years? Bioengineer Karsten Temme discovered a remarkable answer to this ...
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- 00:08This jar contains a few ounces of soil.
- 00:11It looks pretty ordinary, doesn't it?
- 00:14But what you can't see is that it's teeming with life.
- 00:18The microbes inside are poised to become farmer's greatest tool
- 00:22and transform how we feed humanity.
- 00:24I'm Karsten Temme, founder of Pivot Bio,
- 00:27and I have dedicated my career to studying these microbes.
- 00:30They can and will revolutionize agriculture.
- 00:34Give me a sec while I set this down.
- 00:38So from the plow to the grain combine,
- 00:40humans have invented tools to grow more on the same amount of land.
- 00:44Fertilizer is the greatest of these.
- 00:47All those nutrients that a plant combines with sunlight to grow.
- 00:51Here's an example.
- 00:52In the 1950s,
- 00:54American farmers produced 2,600 kilos of corn per hectare.
- 00:59Today, there are yield competitions
- 01:01where the winners can generate more than 32,000 kilos
- 01:04on the same amount of land,
- 01:06in a large part because of the fertilizers
- 01:08they can use to fuel that crop.
- 01:10It's just amazing.
- 01:12But for all the good it does,
- 01:13fertilizer is an inelegant solution.
- 01:16Last year, farmers around the globe spent more than 200 billion dollars
- 01:20on nitrogen fertilizers alone.
- 01:22They spray it on their fields
- 01:24and then pray that roots can find it
- 01:26before it's lost.
- 01:29Because if that fertilizer is lost,
- 01:30the crop can end up starved of its nutrients
- 01:33and stunted in its yields.
- 01:36Those losses also translate to unintended consequences.
- 01:41Some becomes nitrous oxide,
- 01:43a greenhouse gas that's 265 times more potent than CO2.
- 01:47Some seeps into our groundwater.
- 01:50And some runs into our rivers and oceans,
- 01:52creating more than 500 dead zones around the planet.
- 01:57So there's got to be a better way.
- 02:01And I'm here today to tell you that there is.
- 02:03And it's rooted in biology.
- 02:04You see, 78 percent of the air around us is nitrogen gas.
- 02:07That's a form that plants can't use,
- 02:10and so they've partnered with microbes on a process called nitrogen fixation.
- 02:14The microbes can breathe in that nitrogen gas
- 02:17and turn it into a form that plants can metabolize.
- 02:20It's a symbiosis, a partnership that's worked for millions of years,
- 02:24right up until the point that humans started breeding crops
- 02:27to be more productive.
- 02:29Those bigger yields needed more nutrients,
- 02:31and fertilizer was invented to fill the gap.
- 02:35Well microbes in response shut down that nitrogen-fixing function,
- 02:39putting those genes into hibernation.
- 02:42What if we could wake them back up?
- 02:45What if we could use modern tools like gene editing
- 02:48to bring those microbes back to being specialized helpers for farmers?
- 02:53Then we could have a way for those microbes to live with the plant
- 02:58alongside the roots,
- 03:00sensing the crops nutrient needs and responding in real time.
- 03:04Well that’s a challenge that I set out to pursue two decades ago,
- 03:08along with my friend, lab mate and cofounder, Alvin.
- 03:11We made it our mission to get those genes working again.
- 03:16So here's how that went.
- 03:18We collected soil samples from farms across the United States.
- 03:23We extracted the microbes, we reprogrammed their DNA,
- 03:25and we cranked that nitrogen- fixing function to 11.
- 03:29Then one day in the lab,
- 03:30we saw that there was a test tube with a tiny corn seed germinating.
- 03:35Our microbes were living along the roots of that plant,
- 03:39producing nitrogen and sharing it with that tiny plant.
- 03:42That test tube represented a breakthrough.
- 03:44We had shown that we could create microbes
- 03:47that could sense and respond to the plant's nutrient needs
- 03:50in real time.
- 03:51We thought we had just solved agriculture.
- 03:54Well, spoiler alert, not quite.
- 03:56Across the last 15 years,
- 03:58we have been working to transform this breakthrough into a system
- 04:01that serves farmers on three continents today.
- 04:04I believe that across the next decade,
- 04:06we can help farmers reduce half of the fertilizer that they need.
- 04:11So what I wanted to do is take you on a quick little journey
- 04:14to meet three of the farmers that are using these microbes right now.
- 04:18So meet John.
- 04:19He's a corn farmer in Michigan who runs a 1,295-hectare farm.
- 04:24It's a complex operation, and he's got a lot of variables to manage
- 04:27so he doesn't need anymore.
- 04:29John’s turned to Pivot for the last five years to simplify his life.
- 04:33Each year we've sent him a little less than four kilograms of freeze-dried,
- 04:37powdered microbes,
- 04:39and he's coated the seeds with microbes,
- 04:41planted them as normal.
- 04:43Once in the ground, those microbes have gone to work.
- 04:46They eat sugars from the crop,
- 04:47they fix nitrogen and share it back with the plants.
- 04:51And then when the crops are harvested, those microbes die,
- 04:53ensuring they only do what we intend.
- 04:55Now they're operating at the cutting edge,
- 04:57alongside satellite mapping and soil monitoring,
- 05:01slow-release fertilizers and precision machinery.
- 05:04It means that yields at John's farm have boomed.
- 05:08His dad regularly applied more than 225 kilos
- 05:11of nitrogen fertilizer per hectare
- 05:13and generated about 8,500 kilos of corn.
- 05:17Today, John's able to apply less than 140 kilos of fertilizer,
- 05:21and yields have risen to 11,500 kilos.
- 05:25On that same land.
- 05:26It's amazing.
- 05:28And what gives me the most pride is that our microbes are helping
- 05:31make his job easier,
- 05:34while increasing his bottom-line profitability.
- 05:37And John's not alone.
- 05:38Our microbes have been used on as much as five percent of the US corn crop.
- 05:43So if you'll zoom with me about 7,000 kilometers south,
- 05:46I'd like to introduce you to Charles.
- 05:49Now Charles runs a large farm in Brazil.
- 05:51Brazil is an agricultural powerhouse.
- 05:54It's one of the world's top three corn producers.
- 05:57Yet, yields average just about 6,000 kilos per hectare.
- 06:01So there's a lot of room for upside improvement.
- 06:03One of the biggest limiting factors is nitrogen fertilizer.
- 06:07Brazil imported more than 80 percent of its nitrogen fertilizers last year.
- 06:12And that's something it's looking to reverse through microbes,
- 06:15both with us and others.
- 06:17So Pivot's been working with the Ministry of Agriculture
- 06:20to test and adapt our products ahead of commercial sales.
- 06:24And I'd like to give you a little bit of a look into Charles's farm,
- 06:27where he's counting on those microbes to supply about 30 kilos of nitrogen
- 06:32alongside the 120 kilos of nitrogen fertilizer
- 06:36he's applying every acre.
- 06:37That's about 25 percent less than he normally would use.
- 06:41Now the crop’s a couple weeks away from harvest,
- 06:43but what you'll see is the plants are larger, greener,
- 06:46they're healthier, they've got bigger root systems.
- 06:50All that sets up the crop to be more resilient
- 06:53in the face of an unpredictable climate.
- 06:55It also means that's a bigger factory for producing higher yields
- 06:59at better profitability.
- 07:01This is a boon for Charles's operation.
- 07:03It's also an opportunity for Brazil to have strategic independence,
- 07:07because these microbes can be brewed like beer close to the farm.
- 07:11That means no more reliance on foreign chemicals
- 07:14or global supply chains.
- 07:16We're also working in Kenya.
- 07:18And I'd like to introduce you to Margaret.
- 07:20Now every morning, Margaret wakes at 4 am
- 07:22and as she walks five kilometers to reach her small plot of land.
- 07:25For her,
- 07:27fertilizer isn't just an expense, it's a significant investment.
- 07:3136 dollars for a 50-kilo bag.
- 07:34She applies it by hand and then prays that the rains don't wash it away,
- 07:37because all it takes is one rainstorm
- 07:40and that investment is washed away.
- 07:43And with it, her family's security is upended.
- 07:46So this is where the limits of fertilizer are most apparent,
- 07:49where there's no margin for safety.
- 07:52So what Pivot's done is we've teamed up with MIT
- 07:54and local partners
- 07:56to adapt our product and supply chain
- 07:58to work for smallholders like Margaret.
- 08:01We've shrunk our packaging.
- 08:03We've built a just-in-time network
- 08:05where farmers can text the day they're ready to plant,
- 08:08and we can motorbike them the freshest microbes possible.
- 08:11The results are astounding.
- 08:13Not only are the crops more resilient to those rainstorms,
- 08:17yields have improved 60 percent.
- 08:20(Applause)
- 08:24You know, the biggest complaint we've received
- 08:27is farmers say,
- 08:28"You haven't told me what the product is or where I can buy it."
- 08:32So I started with this jar of soil.
- 08:39The microbes inside have already transformed how fertilizer works
- 08:43across millions of hectares,
- 08:45making it smart, dynamic, living.
- 08:49Since 2022,
- 08:51farmers have been able to prevent more than 1.3 million metric tons
- 08:55of greenhouse gases.
- 08:57What's needed next
- 08:58is to be able to scale this system across hundreds of millions of hectares.
- 09:03And here's what that's going to require.
- 09:05It's going to require creating a global network for microbial manufacturing.
- 09:10But it's different than building fertilizer factories
- 09:13that cost billions of dollars.
- 09:15Biomanufacturing can scale at one two-hundredth the cost.
- 09:20It also gives us an opportunity to rethink supply chains
- 09:23to make them local and flexible.
- 09:25So in Michigan, that might mean FedEx is the best way
- 09:28to deliver those microbes,
- 09:30and a motorbike in Kenya might be the best last-mile solution.
- 09:34And what excites me the most
- 09:36is that we can spread a web of agronomic knowledge
- 09:39to connect farmers like Margaret, Charles and John together,
- 09:43helping them share knowledge with each other
- 09:45on the best way to put these microbes to work,
- 09:48to not just increase yields,
- 09:50but to improve efficiency and profitability.
- 09:53You see, when we build infrastructure on top of these microbes,
- 09:57we're not just deploying a new type of product.
- 10:00We're building a better way of farming,
- 10:03one that works with nature and not against it,
- 10:05helping farmers grow more with less.
- 10:09Soil is our oldest agricultural technology,
- 10:12and it's the next frontier.
- 10:15With the microbes in here,
- 10:17we can empower farmers to grow the future
- 10:20from the ground up.
- 10:21Thank you.
- 10:22(Applause)