What to Do When You’re Told There’s Nothing Left to Try | David Fajgenbaum, Kiah Williams | TED
What do you do when the world declares something impossible? When physician-scientist David Fajgenbaum was dying from a rare disease and social entrepreneur Kiah Williams was confronting the realities of economic hardship, they began asking a different question: What can I do today? In this conversation, they discuss how turning hope into action can drive meaningful change — one step at a time. (This conversation is hosted by The Audacious Project’s Alexandra Tillmann) (Recorded at TEDNext 2025 on November 10, 2025.)
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- 00:03Alexandra Tillmann: Alright, David, Kiah, thank you so much for being here.
- 00:09Let's jump in.
- 00:10Can you both share
- 00:12when you realized that life couldn't just happen to you,
- 00:17that you had to actively start choosing a path forward?
- 00:22David, I'll start with you.
- 00:23David Fajgenbaum: Sure.
- 00:24I might start back when I was a medical student.
- 00:27I had promised my mom that I would become a doctor in her memory
- 00:30when she passed away,
- 00:31when I was 19 years old,
- 00:32and in my third year of med school,
- 00:34I was really on my way to making that progress,
- 00:37helping patients in my mom's memory
- 00:38when I personally became critically ill with a disease
- 00:41called Castleman disease.
- 00:42I was so sick that I had my last rites read to me,
- 00:45I spent six months in the intensive care unit,
- 00:47and my doctors told me that we were out of options,
- 00:50but they gave me chemotherapy,
- 00:51seven different chemotherapies all at once.
- 00:53And amazingly, those chemotherapies worked.
- 00:56They saved my life, but what they also did
- 00:58is they opened my eyes up to this idea
- 01:00that none of those seven chemotherapies were made for my disease,
- 01:03but they saved my life.
- 01:05So when I relapsed a year later, my doctors told me,
- 01:07"We're out of options, you're going to die from this disease."
- 01:10I said, wait a minute, didn't you give me these seven chemotherapies
- 01:13that weren't made for my disease and they worked?
- 01:16How do we know there's not another drug out there
- 01:18that could help me?
- 01:19And so this sort of opened up my eyes.
- 01:21I eventually discovered another drug that could save my life,
- 01:24but opened my eyes up to this idea
- 01:26that even when the world thinks there are no more options, no more hope,
- 01:29sometimes there's a solution that's literally as close to you
- 01:32as your neighborhood pharmacy.
- 01:33Kiah Williams: I think for me, it was when I was young,
- 01:36my family just fell apart.
- 01:37And we were teetering at the edge of poverty.
- 01:40And I remember going outside, I grew up in West Philadelphia,
- 01:44I remember going outside one night and literally saying to myself, like,
- 01:49I have to be the one that saves myself,
- 01:54that creates a new path for myself.
- 01:55And so I'd always, you know, focused on school and trying to do well.
- 02:00But I made this decision at a young age to just say, like,
- 02:02I was like, I need to get out of here and I need to do something
- 02:06and have a better life than this for myself.
- 02:09And the only one who's going to do it is me.
- 02:12That obviously wasn't true,
- 02:14I had a ton of help from like, teachers, even my parents, etc.
- 02:17But I remember being very young, 15 years old, and saying, like,
- 02:22"I've got to do something different,
- 02:24I need to do something different and better"
- 02:26and was able to, like, work really hard, buckle down in school,
- 02:29got a full need-based scholarship to Stanford.
- 02:32And essentially that was the beginning of me recognizing, like,
- 02:35I could harness my own power and try to make something of myself.
- 02:41And I think fast forward years from then,
- 02:43when I was actually working in clinics, in medical clinics,
- 02:47and was going to be the first doctor in my family
- 02:49and would see patients who weren't getting better,
- 02:52doctor leaves the room,
- 02:54it's just me in the room as a health coach,
- 02:56talking to patients about whatever they want to talk about,
- 02:59and learning that sometimes people weren't getting the medicine
- 03:02that they needed because they couldn't afford it.
- 03:04So that's why their blood pressure is still high,
- 03:07their cholesterol is still high, their diabetes is not getting better.
- 03:10And I realized that I wanted to do something
- 03:12that could address that at a root level
- 03:14for those patients who were trying to take care of their health.
- 03:18And just all of these external factors were blocking their ability to be well.
- 03:23AT: You know, as you both talked about,
- 03:25our life is shaped by our circumstances, right?
- 03:29Some more formative than others.
- 03:31You nearly lost your life.
- 03:34And some we can control more than others,
- 03:37but they all contribute to where we head.
- 03:41As I shared, you know, these can be dramatic,
- 03:45or they can be small.
- 03:47David, you know, your near-death experience with Castleman's disease
- 03:51led you to become both patient and researcher really simultaneously.
- 03:55And Kiah, as you just shared,
- 03:58the economic resources of your family
- 04:01that you were born into really affected
- 04:03kind of, what you dreamed for your future.
- 04:06These are the realities of your lives, but you manage to use it
- 04:10for your creative fuel, for your energy.
- 04:13Can you talk a little bit about how you took those things out of your control
- 04:17and used them to expand rather than to contract,
- 04:22which I think can be a very natural experience for some people?
- 04:26KW: I think -- there's a really good quote that one of my co-founders used,
- 04:31and I love this because I think it so speaks to me,
- 04:35"sometimes motivation follows motion."
- 04:38Not the other way around.
- 04:40And so I think sometimes literally
- 04:41just by putting one foot in front of the other,
- 04:44you don't have to have 100 percent of the answer.
- 04:47You can have five percent of the answer.
- 04:49Just start moving towards that.
- 04:51And so I think when we think about this big issue,
- 04:53even of 30 percent of people in the US not being able to get medicine they need
- 04:59because it's just too expensive.
- 05:01We don't have to have all the answers to fix everything now.
- 05:04We can just start on the thing that we know to be true,
- 05:07which is this is a dumb problem,
- 05:09and we know that there's surplus that exists
- 05:11to actually meet some of that need.
- 05:13And let's start moving forward with that now.
- 05:15And I think a lot of that also, just like from my personal experience
- 05:19and just thinking about my own family and kind of where I came from,
- 05:23I mean, my dad always told me this growing up,
- 05:25he was like, you know, my grandfather wasn't literate.
- 05:28And people would ask him like, well, how does he function?
- 05:32And I remember someone asked specifically,
- 05:34how do you drive if you can't see street signs?
- 05:37And my dad told me that his father said to him,
- 05:39"I look at the stars."
- 05:41And so I'm like, if my grandfather can look at the stars to find his way
- 05:46and navigate through streets,
- 05:49what excuse do I have to not do everything I possibly can
- 05:53for the patients that we're serving, and to plot a better life?
- 05:58Look at the stars.
- 06:00AT: It's incredible.
- 06:01And David, how about you?
- 06:02DF: I love that.
- 06:04For me, I think that the moment that that drug sirolimus,
- 06:07which is the drug that ended up saving my life,
- 06:10the moment that drug started working for me,
- 06:12I started seeing my results improving, started feeling better.
- 06:15I just haven't been able to get this question in my mind.
- 06:18If this drug is working for me,
- 06:20how many more life-saving drugs are sitting at our local pharmacy
- 06:23that could treat more patients and more diseases today?
- 06:26And I think exactly as Kiah is saying, you know,
- 06:28once you see something like this, once you experience something like this,
- 06:32whether it's learning about access to medicines or the work we're doing,
- 06:36learning about the fact that there's all these hidden cures
- 06:39that are unmatched,
- 06:40you can't unsee it.
- 06:41Especially when you see the impact that it has on humans,
- 06:44patients that are alive because of these medicines.
- 06:46And so I think, to answer the question,
- 06:48once you see something like that,
- 06:50it's about continuing to push forward and say, OK,
- 06:52maybe this helped me, but can this help the person
- 06:55down the street from me?
- 06:56Can this help someone else in my community?
- 06:58And then when you start seeing that it can,
- 07:01you can just keep asking bigger and bigger questions.
- 07:03Can it help people all over the world?
- 07:05And I think that's so important in guiding us.
- 07:07AT: Kiah, you just were touching on something.
- 07:11You were talking about the fragility of healthcare across the country,
- 07:14which really led you to start Sirum.
- 07:18In your work, you often confront systems
- 07:21that are not easy to change
- 07:24or that aren't fair.
- 07:26And you've witnessed, as you shared,
- 07:29families that are making impossible choices
- 07:31between being able to afford medicine,
- 07:34being able to get food on the table for dinner.
- 07:38These are issues we're all hearing about every day on our news, too.
- 07:43How do you counsel others
- 07:45who see systems working against the greater good
- 07:50or perhaps are plagued by injustice,
- 07:53but wonder, do they really have the power to make any change?
- 07:58KW: I think that's a very timely question.
- 08:01What do you do in your own community?
- 08:02What do you do in this state, what do you do in the country,
- 08:05whatever level you're looking at?
- 08:07And I think Sirum has really shown me the power of getting out there
- 08:13and just getting stuff done.
- 08:15We started as a very ragtag,
- 08:17like, this started as a student project,
- 08:20and has grown now to the largest redistributor of unused medicine.
- 08:23But sometimes it's literally just picking up the phone
- 08:26and calling a local legislator.
- 08:27So, for example,
- 08:29we actually were able to launch a home-delivery pharmacy
- 08:31in the state of Georgia,
- 08:33but the way that that happened
- 08:34was literally we got an email from a retired person in Georgia,
- 08:39and we got one of these emails that was like,
- 08:41it was like all purple font.
- 08:42So we were like, how legitimate is this?
- 08:44Everyone knows those emails that you get in inbound to your like, hello@sirum.
- 08:49And we were like, this may or may not be legitimate.
- 08:51Concerned citizen that says, "Hey, how do I make this happen in my state?"
- 08:55Emailed us in, called his local legislator,
- 08:59got us a meeting with the chair of public health
- 09:03in the Georgia legislature.
- 09:05That was the beginning that was the spark.
- 09:07So I think we can actually trace back in every area that we're working
- 09:12in this country.
- 09:13It was usually just one person who was concerned.
- 09:16It was a concerned pharmacist who saw unused medicine.
- 09:19It was just a random person who read an article about us and said,
- 09:23"I want to do something, what can I do?"
- 09:25And we said, if you can get us a meeting with the state,
- 09:27that would be awesome.
- 09:29And like, from that moment of just them calling their legislator
- 09:33to say, "Hey, I want to see this program happen,
- 09:37we were able to make inroads.
- 09:38So I think that it can feel very --
- 09:41A lot of it is just unclear what is the path forward.
- 09:45Again, you don't have to know every step,
- 09:47but doing something rather than nothing,
- 09:48choosing action over apathy,
- 09:51I think it just bears out.
- 09:53And I've just seen this multiple times, the value of an email or a phone call,
- 09:57and what it can be to changing, fundamentally,
- 10:00the destiny of our organization,
- 10:03but also our ability to serve tens of thousands of more patients.
- 10:08AT: Incredible.
- 10:10David, I'll turn to you.
- 10:13Many people feel like they need permission
- 10:16or like, a dramatic wake-up call
- 10:18to chase their audacious dreams
- 10:22or really affect change.
- 10:26But what would you say to someone who senses this can't be all there is,
- 10:30you know, but isn't sure quite whether or how to show up?
- 10:35DF: Yeah, great question.
- 10:37I think that no matter what you're going through in your life
- 10:40or the challenges you're facing,
- 10:42I think it's worthwhile asking yourself, what am I hoping for every day?
- 10:46What am I wishing for?
- 10:47What am I praying for?
- 10:48Like actually reflect on the things that you're praying for, wishing for,
- 10:52and hoping for every day.
- 10:54And that can oftentimes tell you exactly what you should be doing,
- 10:57because whatever you're hoping for and you're wishing for,
- 11:00that is actually the inverse of what you should be doing.
- 11:03You know, what can you do today, tomorrow, and the next day
- 11:06to create the thing that you're hoping for,
- 11:08to solve the problem that you wish would be solved.
- 11:11And there are a lot of challenges that we face every day
- 11:13that feel insurmountable,
- 11:15and many that truly we have a hard time
- 11:17actually having an impact on.
- 11:19But there are also many problems in our lives
- 11:22that we're hoping for a solution for,
- 11:24that we actually have something that we can do
- 11:26to help to solve that problem.
- 11:28And as Kiah mentioned, it may be that we can call a state legislator,
- 11:33or maybe it's that we can post something on social media
- 11:35to raise awareness about a problem.
- 11:37But there are tangible things we can do.
- 11:39But I think it all starts at reflecting on what are you hoping for?
- 11:43What are you wishing for?
- 11:44And I think that's a great place to start with,
- 11:47what you should be doing every day.
- 11:48AT: Yeah, you call that, in your TED talk, actionable hope, right?
- 11:52That it's not enough to just hope for something more, to say,
- 11:55well, in six months or in a year, right?
- 11:59Maybe talk a little bit about that.
- 12:01DF: That's right.
- 12:02I've realized there's this circuit and it all starts with hope,
- 12:05you know, what are you hoping for?
- 12:06And that hope really needs to drive action.
- 12:09And if that hope drives action,
- 12:10what I found is it often will drive impact.
- 12:12And what does impact do?
- 12:13It gives you more things to be hopeful for, more hope.
- 12:16You create this incredible circuit.
- 12:18Hope, action, impact, leads to more hope, action, impact.
- 12:21And all of a sudden, years later,
- 12:23you're sitting here with these two amazing people and all of you
- 12:26and able to share about an organization, Every Cure,
- 12:28that's saving lives of patients all over the world.
- 12:31But it all starts with that first hope and turns to action and impact.
- 12:35AT: I know we're going to talk about a lot today, but, you know,
- 12:38for Every Cure and Sirum, like, how can people be part of it
- 12:42or support the work that you're doing?
- 12:45DF: Sure, I'm happy to start.
- 12:46Yeah, absolutely.
- 12:48So many of us in this room have received medicines
- 12:52for diseases that they're not approved for to treat us.
- 12:56It's called off-label use.
- 12:57In fact, 20 to 30 percent of all prescriptions
- 12:59in the US every day are off-label.
- 13:01So doctors are trying drugs for diseases they're not intended for.
- 13:04Unfortunately, it happens very randomly
- 13:06and there are a lot more opportunities for those drugs to be used systematically.
- 13:10But it's just not profitable in our system to find a new use for an old drug.
- 13:14Eighty percent of drugs are generic,
- 13:16so unfortunately, the system isn't built for this,
- 13:18to find new uses for medicines.
- 13:19But the reason I share that as background
- 13:21is that that means that most of you all have received a drug
- 13:24for a disease it wasn't intended for, and maybe it helped some of you.
- 13:28You can go to everycure.org/ideas
- 13:29and you can tell us about a drug that you've received
- 13:32that maybe has helped you, that we can look into.
- 13:34We can look into our AI platform to see how is it ranking
- 13:37versus all of our other repurposing ideas.
- 13:39Second is that you can help to support us financially.
- 13:41We run large clinical trials that are very expensive,
- 13:44and we want to reach patients all over the world.
- 13:46And finally, awareness raising is really important.
- 13:49We find treatments for diseases that we never would have imagined,
- 13:52like lidocaine for breast cancer
- 13:54or DFMO for Bachmann-bupp syndrome.
- 13:57And amazingly, the problem for a lot of these medications is just awareness,
- 14:01just getting that drug to the patient.
- 14:03It's a matter of letting patients and doctors know.
- 14:05So helping to spread the word about our work at Every Cure.
- 14:08KW: For us, there is an opportunity, if you have --
- 14:11in some instances,
- 14:12individuals can actually donate their unused medicine
- 14:15as long as they're in sealed containers, unexpired.
- 14:19So there's an opportunity for you to potentially donate.
- 14:22The other thing I would just say is, this is TED.
- 14:24Like, y'all are well-resourced, well-connected individuals.
- 14:28If you want to see us come to your state to bring a full solution
- 14:34for medication access to your state, reach out.
- 14:37AT: You know, going back to what David was talking about, actionable hope,
- 14:40I think that's such an important thread.
- 14:44And Kiah, we were talking yesterday,
- 14:47and I've heard you say before that it's a privilege to do hard things.
- 14:52Kiah also has a new baby,
- 14:54so she's in the thick of doing hard things right now.
- 15:00And something that you also have said is that,
- 15:04really thinking about short-term pain for long-term gain.
- 15:08So maybe talk a little bit, Kiah,
- 15:10about how you kind of, rationalize those feelings
- 15:14of the pain and the gain.
- 15:16KW: So like, hope is a tough concept for me
- 15:18because I am ...
- 15:21I am a probably realistic, pragmatic pessimist.
- 15:26Like, I don't think anyone who's ever worked with me
- 15:28would say "Kiah is a hopeful, optimistic human."
- 15:31Which is kind of a weird thing to say,
- 15:33considering I'm doing social entrepreneurial work
- 15:36and trying to have impact in this world.
- 15:38So like, why am I doing this?
- 15:39And how do I get up every day and continue to do it?
- 15:42And I think a lot of it comes down to like, you know,
- 15:46when you are having personally experienced,
- 15:48when you are living at the edge
- 15:50and you're like, I've just got to put one foot in front of the other.
- 15:53I've got to make sure I have what I need.
- 15:55I have to make sure there's a roof over my head.
- 15:57I have to make sure there's electricity because the electricity got cut off.
- 16:01Like, you're not necessarily thinking about the hopes and dreams of the future
- 16:05that you want to have.
- 16:06You are thinking about living today and making to tomorrow.
- 16:09But I think that in and of itself, I've realized, is a form of hope,
- 16:13because you do not just lay down and die.
- 16:16Candidly, like.
- 16:18And this is something I say to myself
- 16:19because I am not an optimistic person.
- 16:21I'm not a very hopeful person.
- 16:23"Well, Kiah, you have options
- 16:24and hopefully you choose to make this world a better place
- 16:27and to keep going."
- 16:28And I think what you referenced around, like,
- 16:31how do I make this all work in my head,
- 16:33is, at the end of the day,
- 16:36now that I am not in that situation where I am worried about basic needs,
- 16:42like, it's such a privilege to be able to choose the hard things in your life.
- 16:47For so many people in this world that is not a choice that they have.
- 16:51That thing is sitting right in front of them,
- 16:53staring at them every single day.
- 16:56So the fact that I have food on the table, good health insurance,
- 16:59a roof over my head,
- 17:02I get to now choose
- 17:04what are the things that I'm going to take on that are hard.
- 17:08And so like, I reflect on that,
- 17:09especially now being on a stage like this in a room like this,
- 17:13what a privilege it is for me to choose hard things
- 17:17and to go out and tackle those.
- 17:19And all of us in this room,
- 17:21I think mostly, probably, have the ability
- 17:24to choose the hard things that you're going to tackle in your life.
- 17:28So you can choose career, you can choose to start a new job,
- 17:31you can choose to start a new organization.
- 17:33Like, these are all choices that we have, and it's a privilege of choice.
- 17:37And so I think for me, that is what gives me more hope.
- 17:41And that lights a fire under me of this idea of every day I get to wake up
- 17:45and choose to go out into this world
- 17:47and tackle some of these systems of oppression.
- 17:51Systems of inequality.
- 17:53And so like, what a beautiful life that is,
- 17:56to be able to wake up every day
- 17:57and be at Maslow's hierarchy of need at the top,
- 18:01working on self-actualization.
- 18:04AT: David, for people who are navigating
- 18:08some of that crossroads that you're talking about, a big change,
- 18:11maybe it's you want to start an organization or change jobs,
- 18:17but for those of us who might be in that place
- 18:19but feeling a little bit stuck,
- 18:21what small everyday choices or mindsets
- 18:26do you share with people to kind of help them move forward
- 18:29or build like, a more meaningful path?
- 18:31DF: I think there's three things that can really help you
- 18:34during a really tough time.
- 18:36And I learned this from the six months that I spent in the intensive care unit
- 18:40when I was dying from my disease, Castleman's.
- 18:44And the first is that you have to have a vision for what you're fighting for.
- 18:48So you have to be able to actually see what is it that you want
- 18:52and that you're wishing and hoping for.
- 18:53So for me, I was wishing and hoping for a family
- 18:56with my girlfriend at the time, Caitlin.
- 18:58I was wishing and hoping that I would be able to find drugs
- 19:01in memory of my mom and treat patients in her memory.
- 19:03That vision was so important for me as I was struggling to survive
- 19:07for those six months.
- 19:09The second is that you have to have an amazing team of people by your side.
- 19:13My sisters literally held both of my hands
- 19:16eight hours a day for those six months,
- 19:18giving me the strength that I needed.
- 19:20My dad sat with me, my girlfriend was there with me as well.
- 19:23They provided strength and support.
- 19:24And of course, when you think about it from a professional perspective,
- 19:28the team that you have around you is everything, right?
- 19:30It's so important, it is truly everything.
- 19:32And the third is that you have to take things one step at a time.
- 19:36If someone had come to me at the beginning of the six-month period
- 19:39and said, "You're going to suffer the most unbearable pain you've ever felt,
- 19:42you're going to be on the brink of death for six months.
- 19:45You're going to say goodbye to your family."
- 19:47I would have said, there's no way I have the strength
- 19:50to make it for six months.
- 19:51I would have said, "Where's the white flag?"
- 19:53No way I can do that.
- 19:54But taking the approach of one step and one breath at a time
- 19:57helped me so much.
- 19:58I remember there was one point, about 11 weeks into that illness,
- 20:02where my doctors told me that we were out of options,
- 20:05and I started slowing my breathing.
- 20:07It was so painful to breathe and I was starting to let go.
- 20:10And I remember looking up at my sister and everyone else had said goodbye,
- 20:15you know, said goodbye to all the people that I love.
- 20:18And my sister looked at me and said, "Just breathe, Dave."
- 20:21And I remember hearing that
- 20:22and I was like, "You know what?
- 20:24I can do maybe one or two more breaths, let's go."
- 20:26And I did a couple more.
- 20:27I can do a minute of this, I can do an hour of this.
- 20:30And those couple of hours to couple of days
- 20:33were the difference for the time we needed
- 20:35for the chemotherapy to kick in to save my life.
- 20:37And so I think with all these challenges that we face,
- 20:40if you can have the vision for the future,
- 20:42the support by your side,
- 20:43and then really take things one step or one breath at a time,
- 20:46I think we can overcome so much.
- 20:48AT: Resilience is a topic that's been touched on a lot
- 20:51over these last couple of days,
- 20:52and I think that the perception often is that social entrepreneurs
- 20:58or leaders like you are always full of hope,
- 21:01like, always ready to go forward and conquer more.
- 21:06Like, is that how it feels to you?
- 21:08Do you always feel that way?
- 21:10KW: I think I already said no.
- 21:12I'm a very pessimistic human.
- 21:16In a lot of ways, on a daily basis.
- 21:18But I am, it's interesting,
- 21:20I don't know that I have always hope.
- 21:22I know that I have faith.
- 21:24And I know that I have faith, weirdly, in this country.
- 21:28I have faith in humanity.
- 21:30And I think going back to what is the vision that you want to see
- 21:34and what is the world you want to live in,
- 21:36like, it's much better for me,
- 21:39and I can wake up and be happy and recharged thinking about this world
- 21:44and humanity as a race that is ultimately going to save itself
- 21:47than it is to think about this country or humanity
- 21:51as a race that's going to implode and destroy itself.
- 21:55AT: It's helpful to hear.
- 21:56KW: So ... I think, yeah, a lot of us are tired,
- 22:00like, people are tired.
- 22:03And at the same time, like, this is it.
- 22:07Like, I think you had mentioned previously this concept
- 22:10of short-term pain, long-term gain.
- 22:12I think many of us are in this room or watching this talk,
- 22:16because you've had a lot of really cool opportunities to be successful.
- 22:20And I think what we learned from that is delayed gratification oftentimes.
- 22:25To say, OK, you put in these hours studying, you do schooling,
- 22:29you wait for that promotion, you work hard,
- 22:31you put your head down and you grind to get to some next step.
- 22:34And that is great, that is awesome.
- 22:37At the same time, I want to just raise the alarm that we cannot defer life
- 22:43and we cannot think about like, well, you know,
- 22:46right now is really challenging,
- 22:49hopefully five years from now to be better.
- 22:52I think that there is a time in which you have to decide for yourself,
- 22:55when am I in that grind-it-out, delayed gratification.
- 22:59I'm going to just put in the time and then pop my head out later.
- 23:03And when are you going to say to yourself, like, this is my life now?
- 23:07How am I going to make decisions and take new actions that change my life,
- 23:11my family, my community, my world for the better?
- 23:15AT: I find that so powerful.
- 23:17David, anything you want to add to that?
- 23:19DF: I just completely agree with Kiah in everything she said.
- 23:23I think I probably fall on the end of the spectrum of being
- 23:26maybe a little bit more optimistic and hopeful.
- 23:28Which I think is great,
- 23:30I think the important thing is that it's finding some balance.
- 23:33I think it's important that we get to work together and do tough things.
- 23:37But I think that what I would say is that I sort of, you know,
- 23:42have the mindset of what's possible in terms of treating patients
- 23:45with horrible, deadly diseases.
- 23:47And I get a chance to see people that said goodbye to their family,
- 23:50that were on their last legs
- 23:52and were able to save their life
- 23:54with a medicine that wasn't made for that disease.
- 23:56And it's hard for me to put it into words.
- 23:59Just what that means when you get to see someone come back,
- 24:03literally, from the dead,
- 24:04where you literally get to see someone walk their daughter down the aisle
- 24:08on their wedding day,
- 24:09get to hear their child speak to them for the first time.
- 24:13These things are so powerful and they give you so much energy.
- 24:17It's hard to describe.
- 24:19I think another piece of this is
- 24:21when you say goodbye to people you love, and you start to wake up
- 24:24and you're like, oh my gosh, I got another day.
- 24:26Like, this is incredible.
- 24:28It gives a glow to life that's hard for me to overemphasize.
- 24:32At the same time,
- 24:34we also have patients that we're not able to help
- 24:36and patients where we try everything for them
- 24:38and they still die from their disease,
- 24:40diseases that we're working on so hard,
- 24:43and we want treatment so bad and we just can't find them.
- 24:46And so I think that when you bring all those together,
- 24:49it's the excitement of life and the fact that we're all here
- 24:52and it's just amazing,
- 24:54the excitement of being able to help people that shouldn't be here,
- 24:57that are living what we call overtime,
- 24:59but it's also sitting with the pain of the patients we're not able to help,
- 25:02sitting with the pain of the diseases that we're not able to treat yet,
- 25:06and having that pain drive further action.
- 25:09AT: What is one thing that you would leave people with?
- 25:15Or like, an action that people can take to start to like make change
- 25:19in their life starting today?
- 25:21Kiah, I'll start with you.
- 25:23KW: I think we're in an incredible moment
- 25:25where thinking about what really matters to you,
- 25:28what really matters, not the things --
- 25:30There's a million things that everyone says that they care about, right?
- 25:33Because, like, to be a good human, to be a good person,
- 25:36you must care about a lot of things.
- 25:38You must do all the things, you must vote, you must recycle.
- 25:41You must go to see your dentist every six months.
- 25:43Like, there's all these things that we all have to do.
- 25:46I think there's too much.
- 25:48There's so many things.
- 25:49It's so hard to feel like you are a good person
- 25:52that is doing good things.
- 25:55And I think this is a time -- I've really been thinking about this
- 25:58because I have a new priority, which is I have a child now.
- 26:01It's how do I focus on the things that actually really matter?
- 26:06And for me, it’s understanding more authentically for myself,
- 26:12what are the things that, like --
- 26:14for me, it's again, it's like, what are the things that bother me?
- 26:17What are the things that anger me,
- 26:19what are the things I'm excited about?
- 26:20Like, for me, it's all about the strong emotions that come out
- 26:23and how do I focus my life and my work and my mission on impacting those.
- 26:29And it's going to have to be, for me, the way I choose to do that,
- 26:32is going deep in a couple areas and having to maybe say,
- 26:36I maybe didn't go to the dentist in the last six months
- 26:39and like, I'm OK with that.
- 26:41Like, maybe I'm taking a break from some of these things
- 26:44because I want to focus on these others.
- 26:46So I think it's really just understanding for you
- 26:48what are the things that actually just deeply matter
- 26:50and taking action on those
- 26:52because it's the recognition you can't do everything.
- 26:54And I'm a person who wants to do everything.
- 26:56And so I think rather than being really sad about that,
- 26:59it's using that as the empowering statement to myself
- 27:02to say, I can't do everything but the things I'm going to do,
- 27:04I'm going to do really well,
- 27:06I'm going to be really focused
- 27:07and I'm going to see impact in those areas.
- 27:10AT: But it is very important to go to the dentist every six months,
- 27:13don't forget that.
- 27:15David, just quickly.
- 27:16DF: Sure, so, completely agree with Kiah's points.
- 27:19And one way that I've sort of framed this
- 27:22in a way that's been really helpful for me,
- 27:24is that I've considered the moment that I nearly died for the first time
- 27:28to be the start of my overtime.
- 27:29And overtime is a sense that many of us can relate to.
- 27:32So think about at the end of a sporting event
- 27:35where your game goes into overtime,
- 27:37and if you're playing in one of those games,
- 27:40it can be really scary to be in overtime
- 27:42because like, at any minute, the game could end,
- 27:44if you make a mistake in overtime, the game is over.
- 27:47Make a mistake in the first half the game, you can make up for it.
- 27:50So overtime can be really scary.
- 27:52But overtime can also be really clarifying.
- 27:54When you're in overtime,
- 27:56you focus only on the things that are most important to win,
- 27:59whatever that sporting event is.
- 28:00And so I found for me
- 28:02that I've been in the state of overtime now for 15 years,
- 28:04I guess I'm in my fifth overtime by now.
- 28:07But in this overtime, it helps me to sort of cut out the noise,
- 28:10the things that I don't care about, the things that aren't important to me,
- 28:14and to just focus on the things that are really important to me.
- 28:17And so I think that I've, when I was 25,
- 28:19sort of first realized that we're all in overtime.
- 28:23But the truth is, we're all in overtime.
- 28:26And, you know, none of us know how long our overtime is going to go for.
- 28:29But all of us have the ability to make the most of every second in overtime.
- 28:33AT: What a great way to end.
- 28:34David, Kiah, thank you so much for a great conversation.
- 28:37(Applause)